Graham Potter has the new challenge of trying not to drop too many players who are off the back of good performances against Borussia Dortmund.
In an ideal world, the manager would probably play the exact same team again in order to look to go for three wins in a row.
However, with an eye to keep everyone fit for the future round of the Champions League, we believe rotation may be in order again this weekend.
GK and Defence
Kepa made a couple of notably good saves against Borussia Dortmund, which will do his confidence positives as he looks for three consecutive clean sheets.
Wesley Fofana has enjoyed a dominant couple of starts in a row, and will continue on the right of defence on Saturday.
With him not being eligible for Champions League games, Benoit Badiashile will return to the starting line-up in the Premier League.
After a man of the match display, Marc Cucurella will be handed another appearance on the left of a back three.
Midfield
Keeping Reece James fully fit is imperative, so Ruben Loftus-Cheek will be handed a start as a makeshift wing-back.
Enzo Fernandez has looked far more comfortable in the new system, and will start again in midfield on Saturday.
He will have his latest new partner in the defensive minded Denis Zakaria alongside him.
Ben Chilwell was superb against Dortmund, and will start again as a marauding wing-back.
Attack
Raheem Sterling found the net in the week, and will look to become a more regular goalscorer for the Blues with another display at the weekend.
A fantastic false nine display from Kai Havertz makes him almost undroppable for Chelsea this weekend.
On the left, Mykhailo Mudryk will make his first start in five as he looks to get his Blues career up and running.
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